Pesticides and oncogenic modulation.

Interaction of viral oncogenic proteins with the Wnt signaling pathway

It is estimated that up to 20% of all types of human cancers worldwide are attributed to viruses. The genome of oncogenic viruses carries genes that have protein products that act as oncoproteins in cell proliferation and transformation. The modulation of cell cycle control mechanisms, cellular regulatory and signaling pathways by oncogenic viruses, plays an important role in viral carcinogenes...

XWH - 09 - 1 - 0109 TITLE : Histone Code Modulation by Oncogenic PWWP - Domain Protein in Breast Cancers

Oncogenic PWWP-domain protein WHSC1L1 links the homeobox transcription factor IRX3 in breast cancer” American Association for Cancer Research Annual Meeting in Washington, DC, April 17-21, 2010

Laboratory Tests with Androgenic and Anti- Androgenic Pesticides – Comparative Studies on Endocrine Modulation in the Reproductive System of Invertebrates and Vertebrates

The lymphocytic cholinergic system and its modulation by organophosphorus pesticides.

Clinical and basic mechanism observations reveal interactions between neural and immune systems. These two systems create a complex network for recognizing danger to the host and its protection from outside pathogenic elements as well as from inside overreactions of inflammatory character. Here, we review the interactions of these two systems in relation to the effects of pesticides that clearl...

P173: LPS Preconditioning Declines Oncogenic Factors and Inflammatory Responses in PC12 Cells

The release of molecules from injured tissue leads to produce inflammatory response that can result in apoptosis and cell death. Preconditioning (PC) can decrease the inflammatory response, increase neuroprotective mechanism on different levels. So, we investigated the role of PC as a suitable preventative approach in neurodegenerative disease in and inflammatory oncogenic factors in PC12 cells...